What are the functions of the luminescent reagent acridine ester ME-DMAE-NHS?

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Acridine ester ME-DMAE-NHS is an important chemiluminescence reagent with unique chemical structure and superior performance, which can be used for labeling and detection of biological macromolecules such as proteins, antibodies, and nucleic acids. Therefore, it has been widely used in biomedical and molecular biology research. Below, we will provide a detailed introduction to its role in various fields.

Acridine ester ME-DMAE-NHS is a light-emitting reagent with a long chain structure. Its main chemical structure is composed of maleimide thioethyl group and dimethylaminoethyl group. This special structure enables it to have strong affinity on biological macromolecules, which can react with amino and thiol groups in proteins and nucleic acids through Nuclear reaction to achieve effective labeling. The role it plays is roughly as follows:

1. Acridine ester ME-DMAE-NHS is often used for labeling proteins and antibodies in biomedical research. It can react with amino groups (Lysine) in proteins and thiol groups (Cysteine) in antibodies to form stable amide or thioether bonds, introducing chemiluminescence labeling into the target protein or antibody. This marker can play an important role in biological analysis, immunoassay and Drug development.

2. Immunoassay is an important biological analysis technology, which is widely used in the early diagnosis of diseases and Drug development. Acridine ester ME-DMAE-NHS can be used to introduce fluorescent labels into antibodies, enabling them to bind to specific antigens and generate fluorescent signals, thereby achieving rapid and highly sensitive immune detection.

3. In the field of protein research, acridine ester ME-DMAE-NHS is also widely used to introduce chemiluminescence labeling into proteins for studying the structure, function, and interactions of proteins. Fluorescent labeled proteins can be tracked in real-time within organisms, thereby better understanding the biological functions of proteins.

4. With the continuous development of biomedical research, it has been found that acridine ester ME-DMAE-NHS also has great potential for application in drug analysis. For example, it can react with drug molecules and introduce chemiluminescence markers into drug molecules, so as to realize fluorescent tracing and monitoring of drugs, providing new methods for Drug development and efficacy evaluation.

Acridine ester ME-DMAE-NHS, as an important chemiluminescence reagent, has broad application prospects in the biomedical field. It achieves efficient labeling of biological macromolecules by reacting with amino and thiol groups in proteins and antibodies. As an advantageous manufacturer of acridine esters, Desheng can provide customers with 6 different functional groups of acridine esters to meet diverse needs and save time and costs. At the same time, due to direct sales by manufacturers, prices can be flexibly adjusted according to the order quantity. If you have any needs, please feel free to contact us!