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- Usage Introduction
- Product advantages
- Commodity name: BTLA Fc tag
- Commodity ID: 1080800626884628480
- 储存条件: It can be stored for one year at 4 ℃ and for two years at -20 ℃
Human BTLA (B- and T-lymphocyte attenuator)
B- and T-lymphocyte attenuator (BTLA), also known as CD272, is a transmembrane glycoprotein with a molecular weight of 35kD, which is a member of the CD28 family of T cell costimulatory molecules. BTLA contains an extracellular region of 127aa, a transmembrane region of 21aa, and a cytoplasmic region of 111aa. Unlike other members of the CD28 family, the Ig domain of the extracellular region of BTLA is type I rather than type V, and it does not form homodimers. In addition, BTLA and TNF superfamily members HVEM, rather than B7 family ligands, interact. The interaction of BTLA and HVEM transmits inhibitory signals to down-regulate the immune response of lymphocytes.
BTLA-his and BTLA-Fc expressed by the company's mammalian cells have high purity and good activity.
BTLA (Fc tag)
Expression host: HEK293
Molecular weight: 50-65 kD
Concentration: 1-2mg / ml
Storage environment: 1 × PBS (pH7.4)
Storage conditions: short-term storage at 4℃, long-term storage at -20℃. Avoid repeated freezing and thawing.
Safety Tips: Not for human experiment