99% of people do not know the anticoagulants that can be added to the blood vessels.
Release time:
2022-10-18
When we go to the hospital for blood tests, we will find that the colors of test tubes are very different, in fact, their colors are different, the role they play is also different. In between, there is a kind of blood vessel for anticoagulant tube, its function is to prevent blood coagulation, the commonly used anticoagulants added in anticoagulant tube are EDTA salt, EDTA dipotassium or tripotassium, heparin, sodium citrate and so on. Next, I will introduce it to you in detail.
Heparin anticoagulant
Heparin is found in liver organs. as mucopolysaccharide sulfate, heparin can strengthen antithrombin to prevent thrombin formation and inhibit platelet aggregation.
Heparin, such as heparin sodium, heparin lithium and heparin ammonium salt, is generally used in clinic to add heparin lithium test tube, although the price is a little more expensive, but its anticoagulant effect is better, just like a certain kind of biochemical components in serum and the use of heparin anticoagulant plasma will have a significant comparison.
EDTA anticoagulant
EDTA anticoagulants include EDTA disodium, potassium, tripotassium and so on. They can chelate with calcium, remove calcium from the reaction point, and block the endogenous or exogenous coagulation process, thus achieving the purpose of blood anticoagulation.
Therefore, EDTA is one of the most commonly used and important anticoagulants in temporary detection, but it will affect platelet aggregation and leukocyte phagocytosis, so it is generally not suitable for platelet function test.
Sodium citrate anticoagulant
Sodium citrate will chelate with calcium ions in the blood to form soluble substances, thus preventing blood coagulation. The coagulation mechanism is that sodium citrate has a good protective effect on coagulation factors, so its activity slows down, so it is often used in the examination of blood coagulation items. It is also used to determine erythrocyte sedimentation rate.
Potassium oxalate anticoagulant
The principle of its action is that oxalate can form calcium oxalate precipitation with calcium ions in blood samples, so it has no blood coagulation function, so it is often used to detect the anticoagulation of blood samples. As long as a certain amount of potassium oxalate solution is added to the tube, slowly rotate so that the solution is distributed around the pipe wall, and then dry it in a drying oven at 80 ℃. Pay attention to the temperature can not be too high, too high easy to make potassium oxalate decomposition and failure, each tube can make 3-5 ml of blood does not coagulate.
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If you have a need for vascular additives, you are welcome to click on the official website for details!
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2023/09/27
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