In the field of clinical laboratory testing, the efficiency of serum sample preparation directly affects the timeliness and accuracy of test results. With the rapid development of testing technology, traditional coagulation techniques are no longer able to meet the growing demand for detection. Enzyme catalyzed coagulation powder, while ensuring sample quality, significantly shortens coagulation time, bringing great progress to clinical testing work. This technology not only improves work efficiency, but also provides strong support for emergency testing and rapid diagnosis of critically ill patients.

coagulation powder

The mechanism of action of enzyme catalyzed coagulation powder

The core advantage of enzyme catalyzed coagulation powder lies in its unique enzymatic mechanism of action. Unlike ordinary coagulants that rely on physical activation, enzyme catalyzed coagulants directly activate coagulation factors through specific enzyme components, accelerating the entire coagulation cascade reaction in a biocatalytic manner. This mechanism of action makes the coagulation process faster, more efficient, and more precise in activating coagulation factors. The molecular level action mode of enzymatic coagulation can selectively accelerate the formation of fibrin without affecting other components of the blood.

The influence of temperature on the efficiency of coagulation powder

The ambient temperature is an important factor affecting the efficiency of enzymatic coagulation powder. Under suitable temperature conditions of 20-25 ℃, the enzymatic coagulation activity reaches its optimal state and can fully exert its efficient coagulation promoting effect. This temperature range can ensure the activity of enzymes and maintain the stability of blood samples. When the ambient temperature is below the ideal range, the activity of enzyme catalyzed coagulation powder will be significantly affected. Low temperature can slow down the catalytic rate of enzymes and prolong clotting time.

The importance of standardized addition of coagulation promoting powder

The precise amount of addition is a key factor in ensuring better performance of enzyme catalyzed coagulation powder. According to standard requirements, 20-25 μ L of enzyme catalyzed coagulation powder needs to be added for every 2-5ml of blood sample. This addition amount is a scientifically validated ratio that can ensure coagulation efficiency while avoiding the potential impact of excessive addition. Insufficient addition will directly affect the coagulation effect and prolong the clotting time. In practical operation, it is necessary to strictly follow the standards recommended by the manufacturer to ensure that each sample can achieve consistent coagulation promoting effect.

Standard operating procedures for promoting coagulation powder

The standardized operation after blood collection is also crucial for promoting coagulation effect. After blood collection, it should be gently inverted and mixed 5-8 times immediately. This step can ensure that the coagulant powder is in full contact with the blood and evenly distributed in the sample, creating good conditions for the subsequent coagulation process. The gentle reversal method is very important, as it ensures thorough mixing while avoiding violent shaking that may cause hemolysis. Standardized mixing operation can enable the coagulation powder to quickly and uniformly exert its coagulation promoting effect, laying the foundation for the effective initiation of coagulation cascade reactions. This simple but crucial step directly affects the final coagulation effect.

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Enzyme catalyzed coagulation powder can quickly complete blood coagulation

Under ideal conditions, enzyme catalyzed coagulation powder can achieve blood coagulation within 5 minutes, which is significantly shorter than traditional coagulants. This significant time advantage is particularly suitable for scenarios with strict time requirements such as emergency testing and bedside testing. Rapid coagulation not only improves work efficiency, but more importantly, shortens the pre-treatment time of the sample and reduces the possibility of changes in blood components in vitro. Hubei Xindesheng is a professional manufacturer of a full range of blood collection tube additives. Welcome to order and consult!