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BTLA Fc tag
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Dispensable
B and T lymphocyte attenuator (BTLA), also known as CD272, is a 35 kD transmembrane glycoprotein, a member of the CD28 family of T cell costimulatory molecules. BTLA contains 127aa extracellular domain, 21aa transmembrane domain and 111aa cytoplasmic domain. Unlike other CD28 family members, the Ig domain of BTLA extracellular domain is type I rather than V, and it does not form homologous dimer. In addition, BTLA and TNF superfamily members HVEM, rather than B7 family ligands, interact. The interaction between BTLA and HVEM suppresses the immune response of lymphocytes.
BTLA (Fc tag)
Expression host: HEK293
Molecular weight: 50-65 kD
Concentration: 1-2 mg/ml
Purity: > 90%
Preservation environment: 1 x PBS (pH 7.4)
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