In the field of in vitro diagnostics, chemiluminescence technology has become one of the mainstream detection methods due to its high sensitivity and automation adaptability. As a key marker, acridine ester directly affects the performance of the reagent. However, the number of domestic manufacturers with independent synthesis capabilities is limited, and the market has long relied on imported products. In this context, Hubei Xindesheng Material Technology Co., Ltd. insists on independent research and development, gradually establishing a complete technical system from synthesis to quality control, and is steadily growing into an important participant in the field of domestic acridine esters.

acridine ester powder

Why has the domestic supply of acridine esters been restricted for a long time?

The production of acridine esters belongs to the high-tech threshold field, involving multi-step organic synthesis, fine purification, and strict quality control. The entire R&D and production cycle is long, requiring continuous investment in equipment, manpower, and funds. For most companies, it is difficult to see returns in the short term and their investment willingness is low.

At the same time, once customers choose a stable performance acridine ester product, they often use it for a long time and have a weak willingness to replace it. This inertia of use puts significant market promotion pressure on new entrants, requiring a large amount of validation data to gain recognition even if the product performance is similar.

The dual challenges of import dependence and market awareness

For a long time, some users have been inclined to choose imported brands, believing that their technology is mature, batches are stable, and application cases are rich. Although the trend of domestic substitution is evident, building trust requires time to accumulate. New manufacturers not only need to demonstrate product performance, but also provide complete technical support and compliance documents.

In addition, acridine esters belong to segmented raw materials and the overall market size is not large. Without clear positioning and differentiation advantages, enterprises find it difficult to form sustainable business models in competition. Some small manufacturers have withdrawn due to the inability to bear long-term investment, further exacerbating the centralization of the supply side.

Desheng's way to break through: focus and persistence

Faced with industry barriers, Desheng chose to rise to the challenge. The company has established a professional chemical synthesis team, focusing on process optimization and quality improvement of acridine ester markers. After years of accumulation, stable supply of six conventional products has been achieved, covering different water solubility, connection arm length, and reaction activity requirements.

In the production process, Desheng pays attention to the repeatability of each batch, strictly implements purity testing, activity determination, and impurity control processes to ensure the consistency of product performance in actual labeling applications. At the same time, establish a complete testing file and provide CoA reports and other materials to meet customers' requirements for various parameters.

Customized services to meet diverse needs

In addition to the standard product line, Desheng also has the ability to optimize the structure and customize synthesis according to customer needs. For example, to address issues such as insufficient water solubility, low labeling efficiency, or high steric hindrance, the molecular structure or linking groups can be adjusted to enhance compatibility with protein conjugation.

This flexible service model is particularly suitable for customers who are developing new detection reagents or optimizing existing processes. Through small batch testing, technical communication, and feedback iteration, Desheng is committed to becoming a reliable partner in the customer's research and development process, rather than just a raw material supplier.

Using technology to promote domestic substitution and achieve long-term value

Desheng always believes that the independent controllability of core raw materials is the foundation for the high-quality development of the in vitro diagnostic industry. By continuously investing in research and development and improving product quality, the company hopes to provide the industry with reliable and stable domestic options, reducing dependence on a single import channel.

This technology driven and service-oriented development path is gaining more and more attention and cooperation from enterprises. With the continuous improvement of the domestic IVD industry chain, the localization supply of high-performance chemiluminescence reagent raw materials will usher in a broader space.