Application of N-ethyl-N - (hydroxy-3-sulfopropyl) meta toluidine (TOOS) in creatinine assay kit
Release time:
2025-01-20
In the field of modern medicine, kidney function testing has always been one of the important indicators for evaluating human health status. With the continuous advancement of medical technology, the methods for kidney function testing are also becoming increasingly sophisticated. Among them, the application of N-ethyl-N - (hydroxy-3-sulfopropyl) meta toluidine (TOOS) in the creatinine determination kit provides strong support for the quantitative determination of creatinine content in specimens in vitro due to its high sensitivity.
TOOS powder
TOOS， As a new type of colorimetric reagent, it exhibits excellent colorimetric performance in biochemical reactions due to its unique chemical structure and properties. In renal function testing, creatinine is a crucial indicator. Creatinine is a waste product produced during muscle metabolism, filtered by the kidneys and excreted with urine. Therefore, the concentration level of creatinine in the blood can indirectly reflect the filtration function and excretion ability of the kidneys. Once kidney function is impaired, creatinine will accumulate in the body, leading to an increase in creatinine concentration in the blood. By regularly monitoring the concentration level of creatinine in the blood, doctors can timely understand the patient's renal function status and develop more suitable diagnostic plans.
The application of TOOS in creatinine assay kits is mainly reflected in the process of enzymatic or enzymatic colorimetric detection of creatinine. This method is based on the principles of enzymatic reaction and colorimetric method, and indirectly determines the concentration of creatinine by measuring the absorbance of the reaction mixture. During the detection process, TOOS acts as a chromogenic substrate and interacts with reagents such as peroxidase and 4-aminoantipyrine to form a highly sensitive and stable detection method. When creatinine in the sample reacts with the reagent, a colorimetric product with a specific absorption spectrum is produced. By measuring the absorbance of this chromogenic product and comparing it with a pre established standard curve, the concentration of creatinine in the sample can be calculated.
The advantage of TOOS in creatinine measurement lies not only in its high sensitivity and stability, but also in the longer absorption wavelength of its oxidized products. This feature enables TOOS to identify and determine the content of substances during the detection process, making it easier to obtain accurate results without affecting the composition of the test sample. In addition, the pH range of TOOS solution is wide, suitable for enzyme survival and not easily changed, which also provides more convenience for the detection process.
Product packaging
The TOOS products produced by Desheng New Materials have not only been widely used and recognized in the domestic market, but also exported to multiple regions abroad. Its high-quality products and professional services have won the trust and praise of domestic and foreign customers. In the future, with the continuous development and innovation in the field of biochemistry, Desheng New Materials will continue to leverage its professional advantages and technical strength to make greater contributions to the research and production of TOOS. In the future medical field, TOOS will continue to play an important role and contribute more to the cause of human health.
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