Is there a difference between the potency units IU and USP of heparin?

Release time:

2024-12-03


In the vast world of medical and biological research, the selection and application of each reagent are related to the effectiveness of the product. When faced with heparin, an important anticoagulant, customers often ask a question: What are the differences and similarities between the potency unit IU (G-unit) and USP (M unit) of heparin? Next, let's follow Desheng customer service to see how she professionally answers questions and clarifies doubts for customers.

 

Heparin Sodium powder

 

Customer Consultation: Differences between Heparin IU and USP Units

 

Hello, I am a new customer of Desheng and I am currently preparing to purchase heparin sodium for our research project. While reading the product instructions, I noticed that the potency units of heparin are both IU and USP. I am not sure about the specific difference between the two, will this affect my experiment? I hope you can explain it in detail

 

Desheng responds quickly and provides professional answers

 

Thank you very much for your inquiry. Desheng is always committed to providing customers with detailed information and support. Regarding the heparin potency units IU and USP that you mentioned, there are indeed slight differences between the two, but they can usually be considered equivalent in practical applications. Let me explain in detail for you:

 

The international unit of potency for heparin, IU, is the international unit used to measure its activity, while the USP unit is based on specific potency measurement standards set by the United States Pharmacopeia and is mainly used in the US market. According to pharmacopoeia regulations, the international unit (IU) is 6.4% higher than the USP unit, which means 1IU=1.064USP. In practical applications, since this deviation is less than 10%, in most cases, the two are considered equivalent and simplified to use 1IU ≈ 1USP.

 

Physical and chemical testing, determination of potency

 

Most of the heparin sodium export products produced in our country are tested for their potency using the sheep plasma method. The principle is to observe the coagulation degree of heparin sodium added to sheep plasma with standard and test samples for a period of time. If the standard and test samples are mixed at the same concentration and obtain the same coagulation degree, it indicates that their potency is also the same. This is used to compare and determine the potency from unknown samples.

 

Desheng promises: equal emphasis on technology and service

 

At Desheng, we are well aware of the importance of various performance values of our products for scientific research and medical treatment. Therefore, we not only provide high-quality heparin products that meet international standards, but also pay more attention to answering every customer's questions through timely and professional technical support. Your satisfaction and trust are the driving force behind our continuous progress. Whether it's answering questions about the potency units of heparin sodium or heparin lithium, or the scientific methods for heparin potency testing, Desheng strives to be transparent and thorough, ensuring that you have confidence when using our products.

 

Product packaging

 

Thank you again for your question. If you have any other questions or need further assistance, please feel free to contact Hubei Xindesheng. We can respond quickly and provide professional answers. We firmly believe that professionalism is not only the depth of technology, but also the temperature of service. Looking forward to working together with you to create brilliance on the journey of scientific research.