Fructosyl-amino acid oxidase

Fructosyl Amine Acid Oxidase (FAOD, EC1.5.3.X) belongs to redox enzymes, which can catalyze the oxidation and decomposition of fructose amino acids, producing hydrogen peroxide, glucuronide ketone and corresponding amino acids with fructose amino acids as substrates. FAOD is a D-amino acid oxidase family with FAD as coenzyme. Its FAD domain consists of four alpha helix and two beta folds. Its catalytic activity is substrate-specific.

Glucosylated hemoglobin (HbA1C) glucose is formed by specifically modifying hemoglobin with valine residues at the N-terminal of the hemoglobin beta-chain. HbA1C can reflect the average blood sugar level of human body in the past three months, and is not affected by the fluctuation of blood sugar concentration. It is the gold standard for monitoring, management and control of diabetes mellitus.

Biochemical research: FAOD, as the core catalytic enzyme of HbA1C enzyme detection kit, can specifically oxidize N-terminal glycosylated amino acids to produce hydrogen peroxide, which is coupled with corresponding color sources to produce signals. The FAOD provided by our company is a gene recombinant product. The product without animal-derived virus has high purity and good activity. It can be used as an indispensable raw material for the development and production of HbA1C diagnostic reagent.

Product description:

Formulation: yellow freeze-dried powder, or solution

Preservation buffer: 20 mM Tris-Cl, pH 8.0

Enzyme activity: 75 U/mg

Unit of activity: 1 unit refers to the amount of enzymes required to catalyze the production of 1 umol of H_2O_2 at pH 8.0 and 37 degrees centigrade per minute.

Essential information:

Source: Gene recombinant expression

Molecular weight: 63 kDa (SDS-PAGE detection)

Purity: > 90% (SDS-PAGE test)

Preservation conditions: freeze-dried powder stored at 4 or - 20 for a long time

Transportation Conditions: Low Temperature Ice Bag

Safety Tips: It is strictly forbidden to be used in human experiments.

DeSheng is a veteran blood testing reagent company with 14 years of research and development and production experience. It has a deep research on the raw materials of enzyme preparation. Enterprise friends who need steroid dehydrogenase can directly contact 18062302654 (the same number as Wechat). We look forward to your inquiry!