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immune response
Human OX40 (CD134; TNFSF4)
OX40 (CD134; TNFSF4) is a member of the TNF superfamily and is a type I transmembrane glycoprotein. Human OX40 consists of a signal peptide of 28aa, an extracellular region of 185aa, a transmembrane region of 20aa, and a cytoplasmic region of 41aa. Human OX40 ligand (OX40L / CD 134L) contains 183 amino acids (139 amino acids extracellularly, 21 amino acids transmembrane, 23 amino acids intracellularly). It belongs to the TNF family and is a type II transmembrane glycoprotein. OX40 / 0X40L is an important pair of co-stimulatory molecules, which plays an important role in the body's immune response and various diseases. Immunotherapy by interfering with its interaction has achieved very good results in many animal models. This is The future clinical treatment provides theoretical and experimental basis.
OX40-his and OX40-Fc expressed by mammalian cells of the company have high purity and good activity.
OX40 (Fc tag)
Expression host: HEK293
Molecular weight: 60-72 kD
Concentration: 1-2mg / ml
Purity:> 90%
Storage environment: 1 × PBS (pH7.4)
Storage conditions: short-term storage at 4℃, long-term storage at -20℃. Avoid repeated freezing and thawing.
Safety Tips: Not for human experiment
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Address: C8, Guanggu United Science and Technology City, Ezhou City, Hubei Province
Fax：0711-3704 589
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