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Classification:

Kit materials and others

Add:C8, Guanggu United Science and Technology City, Ezhou City, Hubei Province

E-mail:18062302654@163.com

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  • Description
  • Usage Introduction
  • Product advantages
    • Commodity name: PD-L1 Fc tag
    • Commodity ID: 1080800648283967488
    • 储存条件: It can be stored for one year at 4 ℃ and for two years at -20 ℃

    PD-1 binds to PD-L1, inhibits T cell proliferation, and is an important immunosuppressive molecule

    Human PD-L1

    (programmeddeath- 1 ligand, B7-H1, CD274)

    PD-L1 (programmeddeath-1 ligand), also known as B7-H1, or CD274, is a member of the B7 family of immunomodulatory molecules and is a transmembrane glycoprotein with a molecular weight of approximately 65 kD. Mature human PD-L1 is composed of a 220 amino acid extracellular region (containing 2 immunoglobulin-like regions), a 21 amino acid transmembrane region, and a 31 amino acid cytoplasmic region. The interaction between PD-1 and PD-L1 can inhibit the proliferation of T cells and at the same time inhibit their production of IL-2, INF-γ and IL-10. Recent studies have shown that the use of Anti-PD-L1 mAb in the body can regulate autoimmune diseases. Blocking the interaction between PD-1 and PD-L1 may provide a feasible strategy for future therapeutic regulation of antiviral immunity, antitumor response, and autoimmune diseases.

    PD-L1-his and PD-L1-Fc expressed by our company's mammalian cells have high purity and good activity.

    Human PD-L1 (Fc tag)

    Expression host: HEK293

    MMolecular weight: 68-75kd

    Concentration: 1-2mg / ml

    Purity:> 90%

    Storage environment: 1 × PBS (pH7.4)

    Storage conditions: short-term storage at 4℃, long-term storage at -20℃. Avoid repeated freezing and thawing.

    Safety Tips: Not for human experiment

  • 德晟的试剂盒原料产品有胱抑素C、胱抑素C抗体、血管内皮生长因子、细胞色素P450蛋白、唾液酸、降钙素原抗体、甲胎蛋白等上百种品种。德晟秉承着以德为本、以客为尊、品质至上、技术领先的经营理念,不断在提升和优化自己的产品及服务,只为得到更多客户的肯定。公司拥有强大的技术储备力量以及完整的研发生产、质量管控、销售服务体系,日产量高,可保证充足的现货供应,德晟还设有专业的品质检测部门,对于产品的各项关键指标严格要求,是值得客户信赖的试剂盒原料生产厂家。

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