Characteristics of heparin anticoagulant in blood collection tube

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Heparin anticoagulant is a kind of reagent used for blood anticoagulation. It is usually used for blood collection tube anticoagulation. It can also be used for medical anticoagulation and beauty products. Heparin was first discovered and named from the liver of animals. It is a kind of mucopolysaccharide sulfate. It is a natural anticoagulant substance in the animal body and has unique properties compared with other anticoagulants.


The source of heparin anticoagulant is different from other anticoagulants:

Anticoagulants such as dipotassium EDTA, sodium citrate or potassium oxalate can be directly artificially synthesized or extracted from plants. The sources are relatively wide and the cost of raw materials is not high. The difference between different products is mainly reflected in the purification process and technology; while heparin Anticoagulant is different. It needs to be extracted from the animal body, usually from the small intestine of sheep or pig, and the content is very small. It takes thousands of pigs to extract one kilogram of heparin. There are two main types of heparin anticoagulants commonly used: heparin sodium and lithium heparin anticoagulants.

Heparin anticoagulant bottled heparin sodium

Application characteristics of heparin anticoagulant:

Heparin is a physiological anticoagulant with antithrombin effect, and inhibits the activation of coagulation factors V, VIII, XI and other factors, and promotes fibrinolysis. Heparin anticoagulant is usually its sodium, potassium, lithium, ammonium salt, such as heparin sodium, heparin lithium, etc., of which heparin lithium is the best.


Heparin anticoagulant affects the volume of blood cells and rarely produces hemolysis. It is often used for hematocrit, blood pH, blood gas analysis and other biochemical determinations. It is also suitable for red blood cell osmotic fragility tests. Add 1 mL of a solution containing 1 g/L of heparin to each tube, and dry it below 60 ℃ for later use to prevent 5-10 mL of blood from clotting. Heparin anticoagulation is not suitable for blood smear examination, because it will have a bluish background during Wright's staining, and it is also not suitable for examination of coagulation factors.


Preservation and use of heparin anticoagulant:

Heparin anticoagulant is the same as other anticoagulants. The liquid is easy to absorb moisture or even deteriorate and needs to be sealed for storage. Moreover, because heparin is a mucopolysaccharide, it can provide nutrition for microorganisms, which is conducive to bacterial reproduction. Therefore, new heparin anticoagulant tubes need to be used. The configured heparin solution, the heparin anticoagulant is ready to use.


Compared with other anticoagulants, heparin anticoagulant is more expensive and has better performance for organisms, but it does not mean that it can replace other anticoagulants, but different anticoagulants have different applications in different situations. According to the different needs of blood collection enterprises, Desheng provides a variety of anticoagulants such as heparin sodium, lithium heparin, dipotassium EDTA, sodium citrate, and a full set of blood collection reagents such as serum separation gel, coagulant, and siliconizing agent.