With the continuous development of marine aquaculture, laboratory simulation of seawater environments, and high-end aquatic ecosystems, the demand for high-quality sea crystals (or artificial sea salt) is increasing. Among them, trace element concentrate, as the core component of sea crystal formula, directly determines the growth status and physiological activity of organisms in the water. In this precise system, the selection of buffering agents is particularly crucial. BICINE buffer (N, N-bis (2-hydroxyethyl) glycine), as a high-performance zwitterionic buffer, is becoming an indispensable functional additive in sea crystal trace element concentrates due to its excellent pH stability and biocompatibility.

BICINE buffer

BICINE: Providing a Stable 'Chemical Environment' for Trace Elements

Trace elements such as iron, zinc, copper, manganese, molybdenum, etc. exist at extremely low concentrations in seawater, but play a decisive role in the development of algae, corals, plankton, and juveniles. However, these metal ions are highly susceptible to hydrolysis, oxidation, or precipitation in aqueous solutions, especially during pH fluctuations. Although traditional buffering systems such as phosphates or carbonates have certain effects, they are prone to form insoluble complexes with metal ions, which in turn reduces their bioavailability. BICINE (7.6-9.0) precisely matches the natural pH range of seawater and can effectively suppress pH drift in dynamic environments. At the same time, due to its stable molecular structure and moderate coordination ability, it is not easily interfered with by trace elements, thus ensuring the long-term stability and efficient release of nutrients.

Improve the stability of concentrated solution and extend the shelf life

In the production process of sea crystals, trace element concentrates usually require long-term storage, which places very high demands on the chemical stability of the formula. BICINE not only has excellent buffering capacity, but also has good water solubility, which can maintain molecular integrity in high ionic strength environments. Experiments have shown that in the concentrated solution system with BICINE added, the oxidation rate of iron ions is significantly reduced, the precipitation time of copper, zinc and other elements is delayed, and the overall solution clarity is maintained for a longer period of time.

Support ecological simulation to assist in the upgrading of scientific research and aquaculture

The reproducibility of the environment is crucial in the preparation of scientific grade artificial seawater. The low toxicity and high biological inertness of BICINE make it widely used in highly sensitive scenarios such as cell culture, marine microbial research, and embryo development experiments. When used in sea crystal concentrate, it can help build a chemical microenvironment closer to natural seawater, reducing experimental errors caused by pH fluctuations or metal deactivation. Sea crystal products containing BICINE can effectively prevent coral fading, algae imbalance, and other issues, improving the survival rate and color expression of ornamental organisms.

Product packaging

Hubei Xindesheng: Empowering Marine Technology with Professional Chemical Strength

Behind the application of BICINE is a hardcore competition between raw material purity and batch stability. Hubei Xindesheng Chemical Technology Co., Ltd. has been deeply involved in the field of biological buffering agents for many years. Its BICINE production adopts an independently optimized synthesis process, with a purity of over 99% and extremely low heavy metal residue. The company has established a strict QC quality control system to ensure that each batch of products has highly consistent pH buffering performance, dissolution rate, and chemical stability, providing reliable raw material guarantee for sea crystal manufacturers.