A method for enhancing the cold viscosity of serum separation gel during weather conditions

Release time:

2024-01-10


Serum separation gel is a widely used experimental tool in the biomedical field, used to separate serum and blood cells from blood, providing clear serum samples for further experiments. However, sometimes in colder climate conditions, the viscosity of serum separation gel may increase, affecting its separation efficiency and normal use. Below, we will discuss the methods for enhancing the viscosity of serum separation gel in cold weather.

The effect of cold weather on serum separation gel

In colder temperatures, the viscosity of serum separation gel changes, mainly due to an increase in the viscosity of the substance at low temperatures, which weakens the fluidity of serum separation gel. This takes longer for operators and is not conducive to preparing it into blood collection vessels, resulting in reduced production efficiency.

The reasons for the enhanced viscosity of serum separation gel in cold weather

In low-temperature environments, the viscosity enhancement of serum separation gel is mainly due to the following reasons:

1. Temperature decrease: As the temperature decreases, the molecular activity in the serum separation gel slows down, leading to a decrease in its fluidity and an increase in viscosity.

2. Inter molecular interactions: In low-temperature environments, the intermolecular forces in serum separation gels are enhanced, resulting in a tighter arrangement of molecules and an increase in viscosity.

3. Colloidal particle size and distribution: The size and distribution of colloidal particles in serum separation gel can also affect its viscosity. In low-temperature environments, the interaction between particles increases, leading to an increase in viscosity.

A processing method for enhancing the cold viscosity of serum separation gel during weather conditions

To overcome the issue of increased viscosity of serum separation gel in cold weather, the following methods can be adopted:

1. Heating treatment: Place the serum separation gel in a warm environment and wait for it to return to room temperature, which helps to reduce the effect of low temperature on viscosity and improve its fluidity.

2. Preheating equipment: Before using serum separation gel, professional equipment can be used for preheating. These devices can accurately heat the separation adhesive to an appropriate temperature, ensuring that it can maintain moderate fluidity even in low temperature environments.

3. Water bath heating: Prepare a suitable container and place the serum separation gel inside. Heat the container in a water bath at a temperature of 40-60 degrees Celsius. During the heating process, it is necessary to control the water bath temperature and ensure that the serum separation gel is uniformly heated. The heating time should be based on the uniform temperature of the serum separation gel gel, usually between a few minutes to more than ten minutes. After heating, remove the serum separation gel and operate it quickly. Pay attention to avoiding excessive heating during the water bath heating process to avoid affecting the biological activity of serum separation gel.

In cold weather, the increase in viscosity of serum separation gel is a common problem, but this problem can be effectively overcome by adopting appropriate treatment methods. Heating treatment, preheating equipment, and water bath heating are all feasible solutions. In addition, rapid handling and maintaining indoor environment in experimental operations are also key to addressing this issue.

As a professional manufacturer of serum separation gel for blood collection additives, Desheng provides separation gels with accurate specific gravity, good flipping performance, and minimal viscosity changes. It has also established long-term cooperation intentions with multiple blood collection companies in the market and has been widely recognized and praised. If you are also interested, please feel free to contact us for purchase at any time!