The quality of blood collection tubes directly affects the accuracy of blood samples during medical testing. As a key additive in blood collection tubes, the preparation process of coagulants is particularly important. This article will analyze the necessity of coagulant drying treatment from a technical perspective and explore its impact on the detection results.

blood Coagulants

1、 The effect of undried coagulants on blood samples

Coagulants usually exist in suspension form when added to blood collection tubes. If not dried, the residual moisture will dilute the blood sample, causing deviations in the measured values of blood component concentrations. For example, indicators such as hematocrit and hemoglobin in blood routine tests may be lower than their actual values due to dilution. Moisture can also affect the chemical activity of coagulants. Water molecules may interfere with the interaction between coagulants and coagulation factors, prolonging blood clotting time. This delay will further affect the efficiency of serum separation and cause inconvenience for emergency cases that require rapid testing.

2、 The key role of uniform distribution of coagulants

Undried suspension is unevenly distributed on the inner wall of the blood collection tube, which can easily form local aggregation. This uneven distribution can lead to inconsistent contact areas between blood and coagulants, resulting in differences in clotting time. In batch testing, this difference can interfere with the standardization of the testing process and increase the uncertainty of the results. Uneven distribution may also affect serum quality. Some samples may exhibit hemolysis or residual fibrin, which may affect the accuracy of biochemical testing. For automated detection equipment, this inconsistency will increase the frequency of instrument alarms and reduce detection efficiency.

3、 Technical advantages of drying process

Drying treatment can effectively remove the moisture in the coagulant, forming a uniform solid film that adheres to the pipe wall. This process eliminates the risk of sample dilution while ensuring the stability of coagulant activity. Dried coagulants can maintain a longer shelf life and reduce performance degradation caused by changes in storage conditions. At the technical level, the drying process can optimize the efficiency of coagulants. By controlling temperature and time parameters, coagulants can quickly take effect after blood contact, shortening the time required for serum separation. This controllability provides flexibility for different detection needs, such as quick detection and routine detection, which can use different drying processes for blood collection tubes.

4、 Process improvement and quality enhancement

With the increasing demand for medical testing, the drying process of coagulants continues to improve. Modern blood collection tube production adopts gradient heating technology to avoid the damage of high temperature to coagulant components. The application of vacuum drying technology further improves the efficiency of water removal and ensures the uniformity of the coagulant coating. The optimization of the process is also reflected in the quality control process. By introducing an automatic visual inspection system, the coagulant coating of each blood collection tube can be inspected to ensure consistency between batches. This strict quality control provides assurance for the reliability of the test results.

Product packaging

Conclusion

The drying treatment of coagulants is an important step in the production of blood collection tubes, which directly affects the accuracy of blood testing. By removing moisture and ensuring uniform distribution, this basic process provides reliable assurance for medical testing. With the development of technology, the continuous optimization of drying process will further enhance the performance of blood collection tubes. On the path of pursuing detection accuracy, process details are crucial. Hubei Xindesheng Material Technology Co., Ltd. focuses on the research and development of blood collection tube additives. For more detailed technical parameters, please contact Xindesheng customer service for further inquiries.