High application value of lithium heparin anticoagulant for routine biochemical detection
With the development of modern science and technology, biochemical analysis and detection technology has been widely promoted and applied in the clinic, providing a scientific and reliable basis for the diagnosis and treatment of clinical related diseases. Traditional clinical blood tests mainly use serum as the test standard, but serum testing needs to use serum as the test standard. Before biochemical test analysis, the collected blood samples need to be serum separated, which will affect the timeliness of the test report. Sex. The use of lithium heparin anticoagulated plasma as a test specimen can effectively shorten the time given in the report, and has a higher application value for some critical and emergency patients.
Generally used in clinical routine biochemical tests, non-anticoagulated ordinary test tube specimens are used for testing. No anticoagulant or coagulant is added to the collected blood samples. After the blood has naturally coagulated, the serum is centrifuged or a water bath is used. The serum is separated by centrifugation. The results of this blood biochemical test are relatively stable and scientifically reliable. However, no matter which method is used to complete the test, it takes a long time to separate the serum and complete the test. Moreover, after centrifugation, protein coagulation filaments often hang on the wall or form a fibrous membrane on the surface of the serum, which will adversely affect the measurement of various specimens on the machine. If the blood coagulation performance is not good, the sample needle of the analytical instrument will be blocked, thereby affecting To the relevant inspection results.
Blood collection tube additive—Lithium heparin anticoagulant
After the protein filaments appear in the centrifugation operation, the inspector can only use the glass rod to peel off and then perform the centrifugal treatment. This will not only increase the workload, but also may cause hemolysis of the sample, which will prolong the issuance of the test report. For some critically ill patients, time is life, and the prolongation of the biochemical test report will lead to aggravation of the patient's condition to a certain extent, which is not conducive to the improvement of the success rate of the patient's rescue.
Lithium heparin anticoagulated plasma is used in the biochemical test of routine blood indicators. After the blood sample is collected, it can be centrifuged directly, and the separated plasma is used in the test, which greatly advances the release time of relevant test reports. The experimental results show that the application of lithium heparin anticoagulated plasma and conventional serum separation in the comparison of the results of various biochemical tests, the detection results of the five indicators of serum total protein, albumin, total cholesterol, triglycerides, and high-density lipoprotein cholesterol There is a big difference in the test results of other items, but there is no obvious difference. Therefore, in the routine biochemical tests of lithium heparin, the above five routine biochemical indicators should be tested with serum samples as much as possible, while for other indicators, lithium heparin anticoagulated plasma can be used instead of serum samples for related tests.
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