The role of blood collection vessels containing coagulants in the process of centrifuging serum

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In clinical diagnosis and laboratory research, blood testing is an important means of obtaining information on the physiological status and disease progression of patients. In order to quickly and accurately obtain this information, the coagulant in the blood collection vessel plays a crucial role in the process of blood coagulation and serum separation. This article will delve into the role, application, and precautions of blood collection vessels containing coagulants in the process of centrifuging serum.


blood coagulants


1、 The mechanism of action of coagulants


The main function of coagulants in blood collection vessels is to activate fibrinolytic enzymes, converting originally soluble fibrin into stable fibrin clots. This process is a crucial step in blood coagulation, ensuring the rapid formation of clots in the blood collection vessel, thereby enabling effective separation of serum and blood cells.


2、 Application of blood collection vessels containing coagulants in centrifuged serum


In blood testing, the main purpose of centrifuging serum is to obtain the supernatant after removing blood cells for various biochemical, immunological, and other tests. The blood collection vessels containing coagulants accelerate blood coagulation, shorten the time for serum separation, and improve detection efficiency. In addition, some special types of coagulants can also ensure the stability of the serum, providing reliable samples for subsequent detection and analysis.


3、 Selection of centrifugal conditions


Although coagulants can accelerate blood coagulation, centrifugation is still essential. Choosing appropriate centrifugation conditions (such as time, speed, etc.) is crucial for completely separating serum and ensuring its quality. Different brands and types of coagulants may have different requirements for centrifugation conditions, so in practical operation, it is necessary to carefully read the instructions for blood collection and follow the manufacturer's recommendations.


4、 Centrifuge post-processing and serum quality evaluation


After centrifugation, the serum in the blood collection vessel should be carefully examined and processed to ensure its quality and accuracy in subsequent testing. Firstly, it is necessary to observe whether the serum is completely separated and whether there is any residual fibrin or blood cells. If incomplete serum separation or residual substances are found, re centrifugation or other treatment measures may be necessary. Secondly, for certain special types of testing, such as virus culture or detection of certain biochemical markers, specific preprocessing steps may be required to ensure the applicability of the serum.


At the same time as centrifugation post-processing, the quality of the serum should also be evaluated. The evaluation includes the color, transparency, pH value, etc. of the serum. The changes in these indicators may indicate changes in substances or conditions present in the serum, such as jaundice, hemolysis, or acid-base imbalance. For serum with poor quality, filtration, dilution, or other processing may be necessary to correct any issues.


In addition, the serum after centrifugation should be tested as soon as possible to ensure the accuracy of the results. If immediate testing is not possible, the serum should be properly stored at appropriate temperature and conditions to avoid spoilage or contamination.


Product packaging


Blood collection vessels containing coagulants play a crucial role in clinical diagnosis and laboratory research, as they improve the efficiency and accuracy of blood testing by accelerating blood coagulation and serum separation processes. However, in order to achieve good results, it is very important to choose and use coagulants correctly, master centrifugation conditions, and pay attention to relevant precautions. In the future, with the continuous advancement of technology and the emergence of new materials, we look forward to the emergence of more efficient and reliable coagulants, providing more accurate information and stronger support for clinical diagnosis and treatment.


Hubei Xindesheng Material Technology Co., Ltd. specializes in the production of coagulants and high-efficiency coagulant powders, and customers can choose according to their needs. In addition to coagulants and high-efficiency coagulant powders, Desheng also produces commonly used blood collection additives such as anticoagulants, serum separation gels, and silicides. After more than a decade of research and development and pursuit of quality, the series of blood collection additives has been sold to many regions both domestically and internationally, and is highly recognized by customers. If you are also interested, please click on the official website for inquiries!