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Main applications of carbomer gel
Affected by this year's new coronavirus epidemic, the hand-free gel commonly used in the past is now very popular regardless of whether it is a finished product or a raw material. The carbomers 940 and 980 produced by Desheng are also very popular recently. Now the domestic epidemic is basically controlled , but it is still very serious abroad. Many customers buy carbomer from our company to produce hand-free gel, so what are the carbomer gels used in? The main applications I have compiled are as follows
Carbomer gel use:
1.Eye gels: At present, ordinary eye drops for clinical application have poor drug absorption because the drug stays in the eye for a short time. An ophthalmic gel made of carbomer as a matrix can not only prolong the retention time of the drug in the cornea and increase the absorption of the drug, but also resist high temperature and high pressure while maintaining the release rate and appearance of the drug unchanged. Bron proved that 0.2% carbomer ophthalmic preparations are similar to 1.4% polyvinyl alcohol ophthalmic preparations in safety, but the number of administrations is significantly reduced. The bromine hydrochloride eye drops used in clinical treatment of human dry eye disease has poor efficacy due to its short contact time with the cornea, and the use of a gel made with carbomer 934 has a significant effect of promoting tearing , 1 hour after use will produce maximum effect.
2.Skin gel: Hong Ziguang and others prepared allantoin gel with 1.5% carbomer 940 for the treatment of skin diseases such as dry skin and psoriasis. Clinical results show that the gel is compatible with skin Good, lasting effect and no greasy feeling when rubbed on the skin. Amin et al.'S erythromycin gel prepared with 1% carbomer 940 was used to treat acne. The results showed that the number of acne and the diameter of the base were significantly reduced. Ji Xuesheng et al. Reported that the gel for ultrasound diagnosis developed with Carbomer 940 as the main matrix has the advantages of no irritation to human skin, no damage to the probe, no stains on the clothing, spreading lubrication, suitable viscosity and stable preparation. It has been confirmed by clinical use that the various quality indicators have reached the predetermined effect. In addition, ketoprofen formulations were prepared with 4 different bases, and it was found that the drug was released fastest from the carbomer gel, and the release rate was carbomer gel> hydrophilic ointment> cold cream> white petrolatum , Suggesting that carbomer has a certain role in promoting the transdermal absorption of drugs.
3. Oral gel: Metronidazole is a drug commonly used to treat anaerobic infections and is the first choice for clinical treatment of periodontal disease. According to clinical needs, Wang Xiaomin and others combined the advantages of ofloxacin and metronidazole to develop a compound gel preparation with suitable consistency, no greasy feeling, and easy to apply. The treatment is fast, lasting and easy to use.
4. Carbopol 940, a gel agent for ultrasonic diagnosis, can be used as the main basis for the preparation of the coupling agent. The finished gel agent is non-toxic, harmless and has no side effects on human skin. Appropriate viscosity, stable preparation, etc. Carbopol 940 is used as the main matrix to develop gel for ultrasound diagnosis. After clinical use, various quality indicators have reached the predetermined effect.
Carbomer 980/940 produced by Desheng is simple to prepare, stable in quality and strong in adhesion. Carbomer is a new type of polymer material and a good auxiliary material for drug efficacy. It is the most ideal raw material for preparing gels and has been widely used in pharmacy recently. If you need a buyer, please contact us. Phone: +86 15071057538